I haven't tried any navigation in US, just in Europe and Australia, but all should also have pretty good US coverage. There are many good GPS navigations on the market :
Sygic Aura - try before buy, needs GPU, no problem on DHD
https://market.android.com/details?id=com.sygic.aura&feature=search_result
all others doesn't have trial period :
https://market.android.com/search?q=gps+navigation+USA&so=1&c=apps
I've also tries NDrive 9 (in Europe) and it was good, but new version is not rated well :
https://market.android.com/details?id=com.ndrive.androidusa&feature=search_result
Sometimes I also use Navdroyd, but carefully, this is just very basic and not user friendly (but works at least), maps are compiled from OSM, so they are not so good as commercial ones :
https://market.android.com/details?id=com.osa.android.navdroyd&feature=search_result
Sygic Aura - try before buy, needs GPU, no problem on DHD
https://market.android.com/details?id=com.sygic.aura&feature=search_result
all others doesn't have trial period :
https://market.android.com/search?q=gps+navigation+USA&so=1&c=apps
I've also tries NDrive 9 (in Europe) and it was good, but new version is not rated well :
https://market.android.com/details?id=com.ndrive.androidusa&feature=search_result
Sometimes I also use Navdroyd, but carefully, this is just very basic and not user friendly (but works at least), maps are compiled from OSM, so they are not so good as commercial ones :
https://market.android.com/details?id=com.osa.android.navdroyd&feature=search_result