I would recommend you go try them out in store so you know you can handle the size of the Note 2.
If you can, then it basically comes down to your preferences; if you want significantly more storage (aroune 12 GBs usable vs up to 75+ GBs usable on the Note 2 w/ an SD card), a larger display for content consumption and more productivity (esp. with the S-Pen) and better battery life, get the Note 2. If you prefer a considerably better display, a more manageable sized phone and the fastest CPU/GPU in Android phones at the moment, get the DNA.
It's pretty much that simple. That said, you definitely can't go wrong with this phone. If you've read/watched any reviews for it, you'd see that there's not much to complain about. Which is a tad more than you can say about the DNA from what I've seen.