Though it's equally easy to disable it completely.
In principle you need to unlock the phone to change this, but thanks to Google not thinking it through many phones allow you to use the quick toggles without unlocking. So one suggestion would be to edit your quick settings tiles and remove the location mode tile - that way someone will need to unlock the phone to disable it, and if they manage that all is lost anyway.
(Of course you should remove airplane mode and data toggles too if you want to keep location tools working. That's the problem, security requires inconvenience. And that is why it's stupid to allow quick settings to be used with locked phone - but Google are frequently less smart than they think they are).