@PDN First off my apologies. I never realised the Tab / Box I click from the Windows Tab. that directly opens Outlook Mail (with a Calendar) was actually called Mail and not "for my mail".
I wouldn't listen to a word more from me from here, but can we get to the nub again.
The Mail App then came with Windows (I preferred calling them Programs)
I tried to recreate from an Outlook email link what happens to you.
Is it just Comcast email?
If you click on a link in a Live / Outlook email will that always open in Edge, but not other email addresses you have added to the Mail App.
You can have the Mail app/program open the Chrome browser by default instead of Edge. I checked how.
Is it only You Tube links?
Personally, I have Outlook mail on the Mail app, Yahoo Mail on the Edge browser, with a shortcut box, GMX work mail on an Opera broweer, and Gmail on the Chrome browser. On my phone I have seperate apps for each.
im still struggling with your initial query where Chrome blinks and needs confirmation for a link (from which email) , where Edge opens directly, as it should.
We probably still haven't answered your questions.
Do you want one email program / app to open all addresses?
Admittedly I don't get email notifications on my pc other than the Outlook app, I just open Edge etc and tap Yahoo for example.
Is it just an extra step to Chrome for a link.
Do you paste a link in to Chrome?
I don't know what happens, and a Screenshot from you might contain personal information, so hopefully this will at least bump your questions for someone to see.
Added: Everyone has good experience of their preferences, but here's a recent list of recommended Windows based Email apps from a good source (where email is concerned, they call these email clients - I feel like a 3 year old explaining to a professor) :
https://www.techradar.com/uk/best/best-email-clients