I think that in this case it doesn't matter whether the game is in App Store or Play Market, the question would still be the same.
By mediation I am referring to the mobile mediation platform like AdMob, Appodeal and etc.
Because if you want to monetize your app or game by yourself you need to connect all the ad networks separately but if you use mediation, you have only one SDK with the plugins from many ad networks.
So I was just wondering if anybody here had any experience and can give an advice