1. Shut down phone.
2. Reboot into fastboot / bootloader mode (press and hold BOTH volume-down and volume-up, then press power button until you see the fastboot menu (only takes a second or so))
3. Type in"fastboot oem lock"
If she's rooted or running a custom (inherently rooted) ROM, she could actually re-lock her bootloader with an app (like my Root Toolkit for Android (see my signature for link) or Boot Unlocker) without having to use fastboot. You can also unlock it again with the above apps while you are rooted without wiping the device (where fastboot oem unlock WILL wipe your device).