Help On call. Can I silence all calls except work so I can sleep?

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The Evo is my first smartphone (coming from the Rumor, lol) and I'm wondering if there is a setting or app that can silence all calls except select numbers. I ask because I'm on call at work, and I hate being woken up by other calls - but must leave my phone on while I sleep. Thanks!

 

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Well, I went to their site, it doesn't seem like it will do what I need. Maybe someday though, at least it's possible.