I've been using GO Launcher since before even rooting, I keep it very minimal now days, so minimal some people would wonder why I even bother using it but I'm used to it. I keep it installed on the phone not the card, I don't use transitions, only 1 home screen with only 1 widget (clock, but not GO), only 1 dock line and just a few folders and icons in both the home and app tray. I only have 3 GO themes any more but the icons/dock look really nice and I like the function and look of the folders. It actually performs really well for me (not overclocked). The only time it's slow loading is in booting after being in recovery and did whatever and cleared cache.
There is a minor glich after the last update they had where ocasionally the icons (but not folders) on home screen will delay in snapping into position after rotation and I might let 'em know about that, but this app does constantly change and if it starts getting too bloated and I'm not happy with it I I"ll have to ditch it.