I have had the Samsung Fascinate, Droid Charge (4G), and now since 3 days ago, the Incredible 2. Yes, I actually downgraded from a 4G phone (I have unlimited data) to a 3G phone. The Incredible 2 seems to just work, with very few flaws.
What I noticed my first day with the Inc 2 was how FAST it is. Everything is very smooth and very little lag. The GPS really works, and can even get a lock inside a building. The camera is the fastest Android camera I've used. The screen is a perfect size, not too big, not too small. The form factor overall is excellent, as well as the tactile feel. And battery life is one of the best.
The known drawbacks of this phone are its slightly weaker radio antenna (but don't just look at the bars, look at signal strength in dB), and tinny/weak external speaker. In real use, these don't seem to be much of an issue for most people. At this point I would not take any other phone, all 4G phones included, from Verizon over this phone. Way to go HTC.
P.S. I am not rooted and do not plan to root.