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I don't think everyone is having problems with the 2.2 OTA update.
I don't think everyone is having problems with the 2.2 OTA update. I had my X for 2 days before the 2.2 OTA came out. I know my X was pretty much problem free on the 2.2 OTA.
I've since rooted, manually deodexed, and loaded several roms/themes since. Running ApeX with NexTheme now without any problems.
By the way, I got the Fascinate on release day, and traded it in for an X after a week. Not regretting that choice a bit.
I had an Eris that I had rooted back some time ago so I'm familiar with a lot of the terms but what exactly is deodexed mean?

I would think pre-loaded would have zero problems. Getting an OTA with all the changes we've made to the phone via apps and deleting stuff tends to cause the problems(assuming here)