All Desire's are created equal. There might be small differences in the quality of the battery, and even variations in the voltages required for the internal components, but I doubt it's enough to make one phone last for days while another lasts a few hours.
It depends entirely on how you use it. For example, on Friday morning, I unplugged the phone from the charger, fully charged. I had the day off, and stayed at home over the weekend. So, I only used the phone for a few texts and really quick calls. By Sunday evening, I had to plug it in again.
Today, I once again unplugged it, fully charged. I went on the bus to the train station, then started my 1-hour commute by train, constantly browsing the web and listening to music. Once at school, the phone spent most of the time in standby, I only quickly checked my email a few times during breaks. I then repeated the commute in reverse in the afternoon. By the time I had 10 minutes to my home, the red LED started blinking, after barely 10 hours spent unplugged.
So one charge lasted over 50 hours, the other barely 10. Same phone, same settings and applications installed.