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you honestly should only hafta wipe the cache and dalvik cache, however i usually wipe both of those a few times when doing an update only

For most of the MikG releases, aamikam highly recommends doing a full wipe. A few of his releases had an update zip but for most of the builds, a complete wipe was in order.
So to answer the op's question, yes, do a complete wipe if you're going to flash v2.2 or v2.3![]()